Top 10 Pharma Companies in USA 2016

Published in Top Brands category by MBA Skool Team , Last Updated: June 29, 2016

Pharmaceutical companies are focusing a lot on research and development of drugs for treatment of cancer and rare disease drugs. Pharma companies have a hugely wide spread business across USA due to increasing need for healthcare among the American population. The top American pharma companies include Johnson & Johnson, Novartis, Roche, Pfizer and Gilead Sciences, along with brands like Merck & Co, GlaxoSmithKline, Sanofi, Amgen and AbbVie. Here is the list of the top 10 Pharmaceutical Companies in USA 2016.

10. AbbVie

AbbVie is a very young company. Established in 2013, the company is headquartered in Lake Bluff, Illinois, United States.

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The company has worldwide operations, and Richard A Gonzalez serves as the CEO and Chairman of the company. As of 2015, total 28,000 people work for the company, and the company is active in biopharmaceuticals and small molecule drugs.

AbbVie came into existence as a result of separation of Abbot Laboratories into two companies - Abbot Laboratories and AbbVie. Humira is the most selling product of the company accounting for sales of $14 billion.

In 2015 it AbbVie acquired Pharmacyclics, Inc which is a biopharmaceutical company. The company operates in only pharmaceutical products.

The company had a revenue of $ 22859 million in 2015. This was an increment of more than 22% over last year. Its total profits were $ 5144 million. The market capitalization of the company was at $ 97190 million. In 2015, AbbVie spent around $4.3 billion in research and development. AbbVie recently launched a disease education program - What's Your Sore Spot? This program is aimed to provide education to connect people with hidradenitis suppurativa (HS). This is a chronic skin disease.

Abbvie is also planning to acquire Stemcentrx. Stemcentrx is a cancel drug developer. The deal is around $ 10 billion.


Revenue: $ 22859 million

Net Profit/Loss: $ 5144 million

Market Capitalization: $ 97190 million

9. Amgen

Amgen was originally known as Applied Molecular Genetics and is a global leader in pharma industry.

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It stands at rank 9 in the list of top 10 pharma companies in USA, and the company was founded in 1980 and in 1983 it was named Amgen. Amgen was founded by William K (Bill) Bowes and associates. It is the largest independent biotechnology firm of the world. The company is headquartered in Thousand Oaks, California, U.S.A Robert A Bradway serves as the CEO and Chairman of the company. Most of the business of the company is based in the United States and Europe. The company is expanding its operations in Latin America, the Middle East and Asia. Approximately 17,900 people are employed at Amgen. Amgen is present in more than 100 countries around the globe.

The company had a revenue of $ 21662 million in 2015. It was a growth of eight percent as compared to last year. Its total profits were $ 6939 million. The market capitalization of the company was at $ 124040 million. Amgen has Amgen Foundation to focus on excellence in science education. It has so far donated more than $ 200 million to various nonprofit organizations.

It has a Science Education Programs to provide hands-on experience to more than 2000000 students. By CR Magazine, Amgen was named among 100 best Corporate Citizens.


Revenue: $ 21662 million

Net Profit/Loss: $ 6939 million

Market Capitalization: $ 124040 million

8. Sanofi S.A.

Sanofi was founded in 2004 as a result of merger of two companies - Aventis and Sanofi-Synthélabo.

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Initially the merger was opposed by Aventis but later the negotiations were made and bidding value was increased to 54.5 billion Euros from 47.8 billion Euros. Earlier it was known as Sanofi-Aventis which was changed to Sanofi in 2011. The headquarter of the company is situated in Gentilly, France. Jean-François Dehecq was the founder of the company. Serge Weinberg serves as the Chairman of Sanofi while Olivier Brandicourt is the CEO of the company. Firm is active mainly in prescription sales. More than 1.2 lakh people are employed at Sanofi. Sanofi has approximately 400 subsidiaries of which 14 are the most important subsidiaries.

The activities of Sanofi revolve around three activities –



Animal Health.

Sanofi has a dedicated Animal Health division known as Merial. Sanofi is divided into four global business units - General Medicines & Emerging Markets, Specialty Care, Diabetes & Cardiovascular, Sanofi Pasteur and Merial. Most important pharmaceutical products of the company are - diabetes, cardiovascular disease, rare diseases, multiple sclerosis and oncology.

The company had a revenue of $ 39265.45 million in 2015. Its total profits were $ 4873.23 million. The market capitalization of the company was at $ 114850 million.


Revenue: $ 39265.45 million

Net Profit/Loss: $ 4873.23 million

Market Capitalization: $ 114850 million

7. GlaxoSmithKline

GlaxoSmithKline was a result of the merger of Glaxo Wellcome and SmithKline Beecham.

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Headquartered in Brentford, London the company has a total 96,575 employees, and the company was founded in 2000. Sir Beecham Group was founded in 1843, and it started its operations by producing laxatives. Philip Hampton serves as the Chairman of the company while Andrew Witty is the CEO of the company.

Andrew Witty will retire from his post in 2017. GlaxoSmithKline is active in mainly 3 industries - Pharmaceutical, Biotechnology and Consumer goods.

The company was charged with promotion of anti-depressants for uses which were unapproved. It paid a fine of $3 billion for these charges in July 2012. GSK is not much involved in the production of treatment for cancer and rare diseases. It follows the principle that high priced drugs are not sustainable in United States. Most of the big pharmaceutical companies are investing heavily in developing the treatment of rare diseases, GSK has shut down its R&D in treatment of rare diseases. In 2014, GSK sold its cancer drug business to Novartis in return of Novartis' consumer health care and vaccine business. The company had a revenue of $ 27206.91 million in 2015. Its total profits were $ 9521.22 million. The market capitalization of the company was at $ 99600 million.


Revenue: $ 27206.91 million

Net Profit/Loss: $ 9521.22 million

Market Capitalization: $ 99600 million

6. Merck & Co.

Headquartered in Kenilworth, New Jersey, United States, Merck & Co. is at 6th position in the list of pharmaceutical companies in USA.

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Outside US and Canada Merck & Company is known as Merck Sharp & Dohme (MSD). Merck & Co was started in 1891, and this 125 year old company was founded as a subsidiary of the German company Merck, & was founded by George Merck. In 1917, Merck & Co. became an independent company. As of 2015, Merck had a total of 70,000 employees. Kenneth Frazier works as the Chairman and CEO of the company. Merck is credited with developing some of the important vaccines - mumps, rubella, and measles. It also developed a single vaccine for all the three diseases.

The company had a revenue of $ 39498 million in 2015 of which $ 175000 million were generated from its US operations. Its total profits were $ 4442 million. The market capitalization of the company was at $ 149010 million. Merck & Co. started to help people who could not afford medications in 1950s. It has total 7 programs to provide assistance to patients.

Merck is going to acquire Afferent Pharmaceuticals. Merck will pay $500 million in cash for acquisition of outstanding stocks of Afferent. Merck is also planning to acquire companies which produce marijuana based drugs. The company spent $6.6 billion for its R&D in 2015.


Revenue: $ 39498 million

Net Profit/Loss: $ 4442 million

Market Capitalization: $ 149010 million

5. Gilead Sciences

Gilead Sciences is credited with the discovery, development and commercialization of therapeutics.

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The headquarter of Gilead Sciences is situated in Foster City, California, United States, and the company was founded in 1988. Initially the company was involved in the development of antiviral medicines, and ever since the company has grown on to become a global player in the industry. 29 Years old medical doctor, Michael L. Riordan started the company in 1988. A 28 years old company is at 5th rank in the list of top 10 pharmaceutical companies in USA. The operations of the company are distributed in North America, Europe and Australia. Gilead Sciences is active in Biotechnology also other than Pharmaceutics. The main focus of the company was on antiviral drugs.

John C. Martin serves as the Executive Chairman of the company. He has been associated with the company since last 25 years. A total of 7900 employees work for Gilead Sciences as of 2015. Gilead is working continuously towards development of antiviral drug for treatment of HIV/AIDS. The company is working for this for more than 25 years.

In United States, around 70 percent of the HIV patients were prescribed Gillead's products for HIV treatment. Gilead is also attributed to the development of treatment for the liver virus hepatitis C. This treatment has the potential to cure almost 90% of the patients of hepatitis C.

The company had a revenue of $ 32639 million in 2015. Its total profits were $ 18108 million. The market capitalization of the company was at $ 148960 million.


Revenue: $ 32639 million

Net Profit/Loss: $ 18108 million

Market Capitalization: $ 148960 million 

4. Pfizer

Pfizer stands 4th in the list of top 10 pharmaceutical companies of USA.

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The company was founded in 1849 by Charles Pfizer and Charles F Erhart, who were both cousins. Pfizer, which is a global name in pharma industry, is headquartered in New York City, and currently, Ian Read serves as the Chairman and CEO of the company. An expected merger of Pfizer with Allergen plc in was called off in 2016 because of new regulatory rules of United States Treasury. As of 2015, a total 0f 78,300 people work for the company. The company is known for its diversity of employees.

In 2009, the company was found guilty of illegal marketing of Bextra - an arthritis drug. For this it was slapped a fine of $ 2.3 billion. Pfizer produces pharmaceutical product as well as Consumer healthcare products. The majority of the company's revenue comes from biopharmaceutical products. In 2015, Pfizer acquired Hospira, Inc.

The company had a revenue of $ 48851 million in 2015. The revenues saw a decline of 2% as compared to 2014. Its total profits were $ 6960 million. The market capitalization of the company was at $ 202660 million. Pfizer is working in collaboration with Merck & Co. to develop an effective medicine for the treatment of type 2 diabetes. Recently Pfizer announced success in their phase 3 study of the medicine.


Revenue: $ 48851 million

Net Profit/Loss: $ 6960 million

Market Capitalization: $ 202660 million

3. Roche

Roche is a Switzerland based company operating in Pharmaceuticals and Diagnostic divisions.

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Headquartered in Basel, the company was established in 1896, and the company had expertise in production of vitamin preparations and derivatives, and is a globally recognized brand name. The founder of the company is Fritz Hoffmann-La Roche. Roche is also the third largest pharmaceutical company in the world. Roche is the first company of the world that mass-produced synthetic Vitamin C. Roche is the number one company in biotech, oncology, in vitro diagnostics and hospital market. A total of 91,747 employees work for Roche. In 2015 Roche partnered with Foundation Medicine on molecular information. As per Dow Jones Sustainability Indices, Roche is the most sustainable healthcare company in the world. Christoph Franz serves as the Chairman of the Board while Severin Schwan is the CEO of the company.

The company had a revenue of $ 49834.9 million in 2015. Its total profits were $ 9373.87 million. The market capitalization of the company was at $ 238760 million. Roche is the market leader in the in vitro diagnostics business.

A total of 15 billion tests were performed in 2015 using Roche instruments in the world. In order to improve patient care, Roche partnered with Flatiron Health - an industry leader in real world oncology data in January 2016. Roche has a distinction of having 29 medicines listed on the WHO Essential Medicines List in 2015.


Revenue: $ 49834.9 million

Net Profit/Loss: $ 9373.87 million

Market Capitalization: $ 238760 million

2. Novartis

Novartis International AG was founded in 1996, and is a very popular brand name in pharma.

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It was a result of the merger of two companies - Ciba-Geigy and Sandoz Laboratories, where Ciba-Geigy was formed by the merger of CIBA and J R Geigy Ltd. The company is headquartered in Basel, Switzerland and Joseph Jimenez serves as the CEO of the company while Joerg Reinhardt is the chairman of Novartis. As of 2015, the company has an employee strength of 118,700. Novartis products are available in more than 180 countries.

Its count of patents is 972 million. Novartis did acquisition of GlaxoSmithKline’s (GSK) oncology products. The leading divisions of the company are Pharmaceuticals, Alcon and Sandoz. Alcon provides eye products while Sandoz is active in growing generic medicines industry. The Alcon division had disappointing performance which was offset by the strong performance of the company's Pharmaceuticals and Sandoz Divisions. Novartis is targeting growing areas of healthcare to develop innovative products.

The company had a revenue of $ 49440 million in 2015. Its total profits were $ 17794 million. The market capitalization of the company was at $ 210960 million. The innovations at Novartis happens in Novartis Institutes for BioMedical Research. This institute has more 6000 scientists and physicians. Company has unique program Novartis Access. This program is designed for low and middle income countries. It helps the countries to fight against deaths from chronic diseases.


Revenue: $ 49440 million

Net Profit/Loss: $ 17794 million

Market Capitalization: $ 210960 million

1. Johnson & Johnson

There are high chances that you would have used Band-Aid sometime in your life. Band-Aid is associated with Johnson and Johnson.

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Johnson & Johnson tops the list of top 10 pharmaceutical companies in USA, and is a leading pharma brand across the world. Apart from medical devices and pharmaceutical, the company also manufactures consumer packaged goods. Headquarter of Johnson and Johnson is situated in New Brunswick, New Jersey. Johnson and Johnson has around 250 subsidiary companies. Its operations are distributed in more than 57 countries.

Johnson and Johnson was incorporated in 1887 in New Jersey. The company was founded by Robert Wood Johnson, James Wood Johnson and Edward Mead Johnson. The founders of the company were brothers. It began its operations to manufacture surgical dressings. Currently, Alex Gorsky serves as the CEO and Chairman of the company.

The company had a revenue of $ 70074 million in 2015. Its total profits were $ 15409 million. The market capitalization of the company was at $ 287850 million. For fiscal year 2015, the company invested $ 9 billion in research and development.130 years old company's strategies are based on its broad and deep knowledge of the health care landscape. Johnson and Johnson is planning to acquire hair-care company Vogue for $ 3.3 billion cash. It will strengthen the consumer products business of the company. Johnson and Johnson baby powder was alleged to have carcinogenic compound. Taking this into cognizance the Maharashtra Food and Drug Administration (FDA) sent notice to the company in March 2016.


Revenue: $ 70074 million

Net Profit/Loss: $ 15409 million

Market Capitalization: $ 287850 million

Ranking Methodology:

Step 1: Give rank scores to the companies on the basis of

Annual 2015 total revenue, net profit and market capitalization (For end of Dec 2015)

Step 2: Companies with higher figures higher rank score (15-1).

Step 3: Calculate average rank score by weighted average of all the scores (rank score by total revenue, net profit and market capitalization)

Step 4: Weightages given are (0.6 to total revenue, 0.3 to net profit and 0.1 to market capitalization)

Step 5: The higher the average rank score, better the rank. In case of tie of average scores, bank with higher market capitalization is given better rank.

This article has been researched & authored by the Content & Research Team. It has been reviewed & published by the MBA Skool Team. The content on MBA Skool has been created for educational & academic purpose only.

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