Top 10 Pharmaceutical Companies in World 2022

Published in Top Brands category by MBA Skool Team

In this article, we have prepared the list of top pharmaceutical companies in the world 2022 based on business parameter of Revenue. Pharmaceutical industry has been one of the most consistently growing sector the world over.

With billions of dollars riding on the medical industry, top pharma companies have been regularly investing huge sums on research & development to have more innovative solutions in medical sciences. The leading pharma companies have a strong production and distribution of medicines, which are available at all hospitals & pharmacy stores worldwide. 

Top Pharmaceutical Companies by Revenue

The list of top pharma companies include names like Pfizer, Roche, Novartis followed by Merck, Sanofi, Novartis, GSK, J&J, AbbVie etc. Here is the list of the top 10 pharma companies in the world 2022.

Rank 1. Pfizer

American company Pfizer is one of the top pharma companies globally having a massive customer base globally.


Founded in 1849 and with headquarters in New York City, USA, Pfizer, a global pharmaceutical company is ranked 4th in the list of top 10 pharmaceutical companies in the world. Pfizer has an employee count of more than 70000 and is ranked regularly in the Fortune Global 500 Companies list as one of the top pharma companies.

Pfizer had classified its offerings into two business segments: Innovative Products Business and Established Products Business. Under the Innovative Products Business, Global Innovative Pharmaceutical (GIP) segment with medicines in spaces like cardio-metabolic, immunology, neuroscience and rare diseases contributed to more than one-fourth of overall annual revenue and the Global Vaccines, Oncology and Consumer Healthcare (VOC) segment with vaccines contributed to 25% of annual revenue.

Some popular consumer products made by the company are:





During the pandemic of 2020, Pfizer was at the forefront of devising a vaccine for the Covid virus. Along with a few others, it was a leading vaccine provider.

Revenue (USD Billion): 81

Rank 2. Roche

Among the primary top pharmaceutical companies is a leading Swiss-based pharma company, F. Hoffmann-La Roche Ltd.

Image: company website

Roche was founded in 1964 and is headquartered in Basel, Switzerland with over 80,000 employees worldwide. Roche is featured regularly in the Fortune 500 Companies list. Genentech and Ventana are subsidiary companies of Roche. Roche plays in two major verticals, Pharmaceuticals and Diagnostics, with over 40 medicines in the Pharmaceuticals vertical. The Pharmaceuticals Division contributed to more than 75% of the overall annual revenue (majorly contributed by Oncology and Immunology drugs) while the Diagnostics Division contributed to the remaining share of the overall annual revenue. Roche emerges as the market leader in the in vitro diagnostics business and about 15 billion diagnostic tests were carried out worldwide using Roche instruments, globally.

Revenue (USD Billion): 68

Rank 3. AbbVie

AbbVie is an American biopharmaceutical brand that addresses noteworthy master in making little particle medicines for patients around the world.

Image: company website

With its strong focus on research and strategic acquisitions it provides stiff competition to the leading companies in this industry. It recently announced it would acquire the oncology firm Pharmacyclics. Abbvie has more than 25000 employees worldwide. Abbvie is focused on helping people manage serious health conditions. It comprises of scientists, researchers, specialists, and regulatory experts. It has diverse portfolio and a 100+ year old legacy. It has over 40 brands in its portfolio.

Revenue (USD Billion): 56

Rank 4. Johnson & Johnson

Johnson and Johnson is one of the world's most prominent pharmaceutical companies with an immense global outreach.


Johnson & Johnson has an employee count of about 100,000. With an annual revenue of $50 billion, R & D expenditure of $9 billion, Johnson & Johnson is one of the top Pharmaceutical Company in the world. The major segments of business of Johnson & Johnson are: Consumer, Pharmaceutical and Medical Devices. The Consumer segment provides products under the categories like baby care, skin care, over-the-counter drugs, wound care and women’s health, with leading brands like Band-Aid, Benadryl, Neutrogena and Clean & Clear on its portfolio. The Pharmaceuticals segment offers medicines under the verticals of immunology, infectious diseases and vaccines, neuroscience, oncology, cardiovascular and metabolic. Medical Devices are offered for orthopedics, surgery, cardiovascular, diabetes care, surgery and vision care.

Revenue (USD Million): 52

Rank 5. Novartis

The Swiss pharmaceutical Company, Novartis, makes or produces the pharmaceutical products in the zones/area of medicines, pharma products etc.

Image: Wikimedia

Novartis has about 100,000 employees and has a product-reach in over 180 countries. Novartis occupies ranked among the top pharma companies in the Fortune Global 500 Companies list. An annual revenue of more than $50 billion and R & D expenditure of $8 billion make it a strong company. The business areas in which Novartis operates comprises of Pharmaceuticals, Alcon and Sandoz, contributing to 60%, 20% and 20% of annual revenue, respectively. Pharmaceuticals vertical offers innovative and established medicines in verticals like like oncology, neuroscience, retina, immunology and dermatology, respiratory and cardio-metabolic. Alcon caters to a range of eye care medicines under ophthalmic pharmaceuticals and surgical eye care and vision care products as well. Sandoz is the generics division of Novartis, offering retail generics, biopharmaceuticals and oncology injectables and anti-infective.

Revenue (USD Billion): 51

Rank 6. Merck & Co

Merck and Co is a US pharmaceutical company headquartered in New Jersey and is one of the top pharmaceutical companies worldwide.


Merck, an American global pharmaceutical company, with headquarters in Kenilworth, New Jersey, was founded in 1891. Merck has an employee count of about 70000 worldwide. Merck has four major revenue contributors, namely Pharmaceuticals, Animal Health, Alliances and Healthcare Services. The Pharmaceuticals segment is further subdivided into: Primary care and Women’s Health (consisting of drugs for cardiovascular illnesses and diabetes, generic medicines and women’s healthcare products), Hospital and Specialty (consisting of formulations for hepatitis, HIV, immunological disorders and hospital acute care products) and Respiratory divisions.

Revenue (USD Billion): 50

Rank 7. GlaxoSmithKline

GlaxoSmithKline is an English pharmaceutical organization which is known worldwide for its medicines and other products.


GSK’s revenue of more than $45 billion have made it among the top pharmaceutical company in the world. GSK operates in three business segments, namely, Pharmaceuticals, Vaccines and Consumer Healthcare. Each business segment contributing to 60%, 15% and 25%, respectively of the annual revenue. Pharmaceuticals segment comprises of Global Pharmaceuticals with drugs for respiratory, cardiovascular, metabolic and urology, oncology and immuno-inflammation-related illnesses. Vaccines segment had major revenues from various vaccines. Consumer Healthcare segment provides wellness, oral health, skin health and nutrition solutions with major brands like Horlicks, Sensodyne and Eno under its umbrella. The Consumer Healthcare segment represents the Joint Venture with Novartis Consumer Healthcare division and with other related-companies in India and Nigeria.

Revenue (USD Billion): 46

Rank 8. Sanofi

Sanofi is one of the largest pharmaceutical companies in the world having a global presence.

Image: Wikimedia

Sanofi is a French pharmaceutical organization that spotlights on creating and assembling treatments for some of the present greatest worldwide medical problems. Headquartered in Paris, France, the company has a strong workforce with over 100,000+ employees. 

The business areas of Sanofi are focused on attaining three targets:

(a) Sustaining leadership, through formulations for diabetic and cardiovascular disorders, rare diseases, emerging markets and vaccines,

(b) Building competitive positions, through development and commercialization of drugs for multiple sclerosis, oncology, immunology and circulation of consumer healthcare products and

(c) Exploring strategic options, through animal health and generics solutions.

Revenue (USD Billion): 44

Rank 9. AstraZeneca

AstraZeneca, British–Swedish multinational is a leading Biopharmaceutical Company and one of the top pharma companies serving customers worldwide.

Image: company website

AstraZeneca is a British-Swedish global biopharmaceutical company founded in 1999 and headquartered in London, UK. The core business areas of AstraZeneca are classified into (a) Respiratory, Inflammation and Autoimmunity, contributing to 20% of annual revenue (b) Oncology and Metabolic diseases, contributing to 40% of annual revenue(c) Oncology, contributing to 10% of annual revenue and (d) Infection, Neuroscience, and Gastrointestinal, contributing to 30% of annual revenue. New Oncology medicines were introduced, as well, adding to the revenue. During the 2020 pandemic, AstraZeneca was one of the first companies to initiate vaccine research and was one of the first companies to take out the vaccine in several countries, under different brand names.

Revenue (USD Billion): 38

Rank 10. Amgen

Amgen Inc is an American multinational biopharmaceutical organization headquartered in Thousand Oaks, California.

Image: Wikimedia

Amgen finds and creates inventive treatments in both biopharmaceuticals and little particle medicines. The company has more than 20,000 employees worldwide. The company has built a strong legacy since it started 1980. The company has regularly strategized on building molecular biology and biochemistry, with an objective to provide a healthcare business based on recombinant DNA technology.

Revenue (USD Billion): 25

Rank Methodology for Top Pharma Companies

1. The top pharmaceutical companies in the world are considered.

2. Parameters like latest revenues are considered.

3. The brands are ranked by their revenues.

This article has been researched & authored by the Content & Research Team. It has been reviewed & published by the MBA Skool Team. The content on MBA Skool has been created for educational & academic purpose only.

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